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Daniel Mazia

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Name
Area
Years
Daniel Mazia
Daniel Mazia
cell physiology
1979-1997
 

As a cell biologist, Daniel Mazia was known for his work on cell division. In the history of this field, eggs of sea urchins and other echinoderms have been favored material. Large numbers of the eggs, once fertilized will divide synchronously within an hour or so, thus providing abundant samples of cells at a given stage of the division process for any kind of analysis. Mazia's research program, while at Hopkins Marine Station, examined the nature of centrosomes, bodies which define the poles of the dividing cell and which direct the separation of the chromosomes into two nuclei. The studies included the examination of changes of centrosomes during the division cycle, the ways in which centrosomes move apart to form poles for division, and the formation of connections between centrosomes and chromosomes which assure the accurate separation of genetic material to the two daughter cells. Mazia's research included an analysis of artificial parthenogenesis (development of eggs without fertilization), which was discovered at Pacific Grove by Jacques Loeb at the beginning of the century. In normal fertilization, centrosomes are introduced by the sperm cell; it was thought that egg cells had no centrosomes.

 
 
 
Publications:

Cold-treated centrosome: Isolation of centrosomes from mitotic sea urchin eggs, production of an anticentrosomal antibody, and novel ultrastructural imaging, ThompsonCoffe, C; Coffe, G; Schatten, H; et al. CELL MOTILITY AND THE CYTOSKELETON Volume: 33 Issue: 3 Pages: 197-207 Published: 1996

T-1, A MITOTIC ARRESTER, ALTERS CENTROSOME CONFIGURATIONS IN FERTILIZED SEA-URCHIN EGGS, ITOH, TJ; SCHATTEN, H; SCHATTEN, G; et al. CELL MOTILITY AND THE CYTOSKELETON Volume: 16 Issue: 2 Pages: 146-154 Published: 1990

MITOTIC POLES IN ARTIFICIAL PARTHENOGENESIS, MAZIA, D. ZOOLOGICAL SCIENCE Volume: 5 Issue: 3 Pages: 519-527 Published: JUN 1988

MICROTUBULES AND CA-2+-SEQUESTERING MEMBRANES IN THE MITOTIC APPARATUS, ISOLATED BY A NEW METHOD, PETZELT, C; HAFNER, M; MAZIA, D; et al. EUROPEAN JOURNAL OF CELL BIOLOGY Volume: 45 Issue: 2 Pages: 268-273 Published: FEB 1988

CENTROSOME DETECTION IN SEA-URCHIN EGGS WITH A MONOCLONAL-ANTIBODY AGAINST DROSOPHILA INTERMEDIATE FILAMENT PROTEINS - CHARACTERIZATION OF STAGES OF THE DIVISION CYCLE OF CENTROSOMES, SCHATTEN, H; WALTER, M; MAZIA, D; et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 84 Issue: 23 Pages: 8488-8492 Published: DEC 1987

THE CENTROSOME - ORGAN OF CELL ARCHITECTURE, MAZIA, D. ZOOLOGICAL SCIENCE Volume: 4 Issue: 6 Pages: 1127-1127 Published: DEC 1987

FINE-STRUCTURAL STUDIES OF THE BIPOLARIZATION OF THE MITOTIC APPARATUS IN THE FERTILIZED SEA-URCHIN EGG .1. THE STRUCTURE AND BEHAVIOR OF CENTROSOMES BEFORE FUSION OF THE PRONUCLEI, PAWELETZ, N; MAZIA, D; FINZE, EM. EUROPEAN JOURNAL OF CELL BIOLOGY Volume: 44 Issue: 2 Pages: 195-204 Published: OCT 1987

FINE-STRUCTURAL STUDIES OF THE BIPOLARIZATION OF THE MITOTIC APPARATUS IN THE FERTILIZED SEA-URCHIN EGG .2. BIPOLARIZATION BEFORE THE 1ST MITOSIS, PAWELETZ, N; MAZIA, D; FINZE, EM. EUROPEAN JOURNAL OF CELL BIOLOGY Volume: 44 Issue: 2 Pages: 205-213 Published: OCT 1987

THE CHROMOSOME CYCLE AND THE CENTROSOME CYCLE IN THE MITOTIC-CYCLE, MAZIA, D. INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY Volume: 100 Pages: 49-92 Published: 1987

BEHAVIOR OF CENTROSOMES DURING FERTILIZATION AND CELL-DIVISION IN MOUSE OOCYTES AND IN SEA-URCHIN EGGS, SCHATTEN, H; SCHATTEN, G; MAZIA, D; et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 83 Issue: 1 Pages: 105-109 Published: JAN 1986

FLUCTUATION OF THE CA-2+-SEQUESTERING ACTIVITY OF PERMEABILIZED SEA-URCHIN EMBRYOS DURING THE CELL-CYCLE, SUPRYNOWICZ, FA; MAZIA, D. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 82 Issue: 8 Pages: 2389-2393 Published: 1985

CENTROSOMES AND MITOTIC POLES, MAZIA, D. EXPERIMENTAL CELL RESEARCH Volume: 153 Issue: 1 Pages: 1-15 Published: 1984

THE CENTROSOME CYCLE IN THE MITOTIC-CYCLE OF SEA-URCHIN EGGS, PAWELETZ, N; MAZIA, D; FINZE, EM. EXPERIMENTAL CELL RESEARCH Volume: 152 Issue: 1 Pages: 47-65 Published: 1984

FLUCTUATION OF THE CA-2+-SEQUESTERING ACTIVITY OF PERMEABILIZED SEA-URCHIN EMBRYOS DURING THE CELL-CYCLE, SUPRYNOWICZ, FA; MAZIA, D. JOURNAL OF CELL BIOLOGY Volume: 99 Issue: 4 Pages: A429-A429 Published: 1984

CALCIUM SEQUESTERING SYSTEM OF THE SEA-URCHIN EMBRYO, SUPRYNOWICZ, FA; POENIE, M; MAZIA, D. JOURNAL OF CELL BIOLOGY Volume: 97 Issue: 5 Pages: A30-A30 Published: 1983

ORIGIN AND MATURATION OF CENTRIOLES IN ASSOCIATION WITH THE NUCLEAR-ENVELOPE IN HYPERTONIC-STRESSED SEA-URCHIN EGGS, KALLENBACH, RJ; MAZIA, D. EUROPEAN JOURNAL OF CELL BIOLOGY Volume: 28 Issue: 1 Pages: 68-76 Published: 1982

EFFECTS OF GRISEOFULVIN ON FERTILIZATION AND EARLY DEVELOPMENT IN SEA-URCHINS - INDEPENDENCE OF DNA-SYNTHESIS, CHROMOSOME CONDENSATION, AND CYTOKINESIS CYCLES FROM MICROTUBULE-MEDIATED EVENTS, SCHATTEN, H; SCHATTEN, G; PETZELT, C; et al. EUROPEAN JOURNAL OF CELL BIOLOGY Volume: 27 Issue: 1 Pages: 74-87 Published: 1982

Memorial Resolution:

 

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