David Epel
Area: development
Years: 1964-2010
David Epel received his Ph.D. in biology from the University of California, Berkeley, where he studied under Daniel Mazia. He joined Stanford University's Hopkins Marine Station in 1965. In 1970, he accepted a position at the University of California San Diego's Scripps Institute of Oceanography. He returned to Hopkins in 1977, where he remained until his retirement as Professor Emeritus in 2009. Epel's research focused on fertilization and development in the marine environment, often using sea urchin gametes. He is the recipient of a Guggenheim fellowship, the Cox Medal for Excellence in Fostering Undergraduate Research at Stanford and the Ed Ricketts Memorial Award for Lifetime Achievement in the Marine Sciences, and is a Fellow of the American Association for the Advancement of Science and the California Academy of Sciences.
David Epel research program at Hopkins Marine Station explored developmental biology, a field whose progress has depended on the use of eggs and embryos of marine invertebrates. Epel is recognized as one of the foremost students of the process of fertilization, and a number of his discoveries have proved to be applicable to the understanding of fertilization in all kinds of animals. He has contributed to our present views on how sperm cells combine with egg cells and of the biomechanical mechanisms by which eggs, often rather dormant cells, are stimulated to start the program of biomechanical activities which unfolds as the development of the embryo is launched by fertilization. The work of his group was directed toward, the radical changes of the cell membrane and other surface components of the egg at fertilization, the role of ions, especially calcium ions and hydrogen ions, in the activation of the egg and the consequent stimulation of the synthesis of proteins. His contributions have been influential beyond the field of developmental biology. The close analysis of fertilization proves to be a valuable source of information about the ways in which changes of the activities of cells are regulated by membranes and ions.
Another focus of Epel's research explored how embryos handle environmental stress. Marine embryos receive scant parental care; they are essentially orphans whose protective strategies must be unique. How do embryos fend off pathogens before they have immune systems? How do they handle toxins? And how do embryos repair DNA damaged by toxins or UV radiation? Embryo cell cycles are extremely fast; can adequate DNA repair occur between cell divisions?
When sperm meets egg—Fifty years of surprises. David Epel. METHODS IN CELL BIOLOGY. Volume 151. Pages; 3-12 Published : JAN 2019
Ecological Developmental Biology: The Environmental Regulation of Development, Health and Evolution. Scott F. Gilbert and David Epel. BOOK. Publisher: Sinauer Associates, Inc. Publishers Published: Jan 2015
Cost, effectiveness and environmental relevance of multidrug transporters in sea urchin embryos, Cole, Bryan J.; Hamdoun, Amro; Epel, David. JOURNAL OF EXPERIMENTAL BIOLOGY Volume: 216 Issue: 20 Pages: 3896-3905 Published: OCT 2013
Virtual Ocean Acidification Laboratory as an Efficient Educational Tool to Address Climate Change Issues. Fauville, G; Hodin, J; Dupont, Sam; Miller, Pam; Haws, J; Thorndyke, M; Epel, D. CLIMATE CHANGE MANAGEMENT. Pages: 825-836 Published: Sep 2011
Activation of Sperm and Egg During Fertilization. David Epel. COMPREHENSIVE PHYSIOLOGY. HANDBOOK OF PHYSIOLOGY, CELL PHYSIOLOGY. Supplement 31. JAN 2011
Multidrug Efflux Transporters Limit Accumulation of Inorganic, but Not Organic, Mercury in Sea Urchin Embryos, Bosnjak, Ivana; Uhlinger, Kevin R.; Heim, Wesley; et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY Volume: 43 Issue: 21 Pages: 8374-8380 Published: NOV 1 2009
ABCB- and ABCC-type transporters confer multixenobiotic resistance and form an environment-tissue barrier in bivalve gills, Luckenbach, Till; Epel, David. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY Volume: 294 Issue: 6 Pages: R1919-R1929 Published: JUN 2008
Efflux transporters: Newly appreciated roles in protection against pollutants, Epel, David; Luckenbach, Till; Stevenson, Charlotte N.; et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY Volume: 42 Issue: 11 Pages: 3914-3920 Published: JUN 1 2008
Apoptosis in early development of the sea urchin, Strongylocentrotus purpuratus, Thurber, Rebecca Vega; Epel, David. DEVELOPMENTAL BIOLOGY Volume: 303 Issue: 1 Pages: 336-346 Published: MAR 1 2007
Embryo stability and vulnerability in an always changing world, Hamdoun, Arnro; Epel, David. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 104 Issue: 6 Pages: 1745-1750 Published: FEB 6 2007
Research article - The genome of the sea urchin Strongylocentrotus purpuratus, Sodergren, Erica; Weinstock, George M.; Davidson, Eric H.; et al. Group Author(s): Sea Urchin Genome Sequencing Consortium, SCIENCE Volume: 314 Issue: 5801 Pages: 941-952 Published: NOV 10 2006
New perspectives on perfluorochemical ecotoxicology: inhibition and induction of an efflux transporter in the marine mussel, Mytilus californianus, Stevenson, Charlotte N.; MacManus-Spencer, Laura A.; Luckenbach, Till; et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY Volume: 40 Issue: 17 Pages: 5580-5585 Published: SEP 1 2006
Using cell and developmental biology to enhance embryo survival in aquaculture, Epel, D. AQUACULTURE INTERNATIONAL Volume: 13 Issue: 1-2 Pages: 19-28 Published: JAN 2005
Nitromusk and polycyclic musk compounds as long-term inhibitors of cellular xenobiotic defense systems mediated by multidrug transporters, Luckenbach, T; Epel, D. ENVIRONMENTAL HEALTH PERSPECTIVES Volume: 113 Issue: 1 Pages: 17-24 Published: JAN 2005
Activation of multidrug efflux transporter activity at fertilization in sea urchin embryos (Strongylocentrotus purpuratus), Hamdoun, AM; Cherr, GN; Roepke, TA; et al. DEVELOPMENTAL BIOLOGY Volume: 276 Issue: 2 Pages: 452-462 Published: DEC 15 2004
Phosphoinositide metabolism at fertilization of sea urchin eggs measured with a GFP-probe, Thaler, CD; Kuo, RC; Patton, C; et al. DEVELOPMENT GROWTH & DIFFERENTIATION Volume: 46 Issue: 5 Pages: 413-423 Published: OCT 2004
Some precautions in using chelators to buffer metals in biological solutions, Patton, C; Thompson, S; Epel, D. CELL CALCIUM Volume: 35 Issue: 5 Pages: 427-431 Published: MAY 2004
Protection of DNA during early development: adaptations and evolutionary consequences, Epel, D. EVOLUTION & DEVELOPMENT Volume: 5 Issue: 1 Pages: 83-88 Published: JAN-FEB 2003
Algal products as naturally occurring substrates for p-glycoprotein in Mytilus californianus, Eufemia, N; Clerte, S; Girshick, S; et al. MARINE BIOLOGY Volume: 140 Issue: 2 Pages: 343-353 Published: FEB 2002
Multixenobiotic resistance, P-glycoprotein, and chemosensitizers, Kurelec, B; Smital, T; Pivcevic, B; et al. ECOTOXICOLOGY Volume: 9 Issue: 5 Pages: 307-327 Published: OCT 2000
NO is necessary and sufficient for egg activation at fertilization, Kuo, RK; Baxter, GT; Thompson, SH; et al. NATURE Volume: 406 Issue: 6796 Pages: 633-636 Published: AUG 10 2000
Induction of the multixenobiotic defense mechanism (MXR), P-glycoprotein, in the mussel Mytilus californianus as a general cellular response to environmental stresses, Eufemia, NA; Epel, D. AQUATIC TOXICOLOGY Volume: 49 Issue: 1-2 Pages: 89-100 Published: MAY 2000
The roles of changes in NADPH and pH during fertilization and artificial activation of the sea urchin egg, Miller, BS; Epel, D. DEVELOPMENTAL BIOLOGY Volume: 216 Issue: 1 Pages: 394-405 Published: DEC 1 1999
The multi-xenobiotic resistance phenotype as a tool to biomonitor the environment, Minier, C; Eufemia, N; Epel, D. BIOMARKERS Volume: 4 Issue: 6 Pages: 442-454 Published: NOV-DEC 1999
Detection of phospholipase C gamma in sea urchin eggs, De Nadai, C; Cailliau, K; Epel, D; et al. DEVELOPMENT GROWTH & DIFFERENTIATION Volume: 40 Issue: 6 Pages: 669-676 Published: DEC 1998
Redox changes during fertilization and maturation of marine invertebrate eggs, Schomer, B; Epel, D. DEVELOPMENTAL BIOLOGY Volume: 203 Issue: 1 Pages: 1-11 Published: NOV 1 1998
Daniel Mazia: a passion for understanding how cells reproduce, Epel, D; Schatten, G. TRENDS IN CELL BIOLOGY Volume: 8 Issue: 10 Pages: 416-418 Published: OCT 1998
Effects of wheat germ agglutinin on tunicate egg activation and fertilization: Is there a plasma membrane sperm receptor system on Ascidia ceratodes eggs? Flannery, B; Epel, D. DEVELOPMENT GROWTH & DIFFERENTIATION Volume: 40 Issue: 3 Pages: 297-306 Published: JUN 1998
Use of multidrug transporters as first lines of defense against toxins in aquatic organisms, Epel, D. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY Volume: 120 Issue: 1 Pages: 23-28 Published: MAY 1998
Bacterial symbionts colonize the accessory nidamental gland of the squid Loligo opalescens via horizontal transmission, Kaufman, MR; Ikeda, Y; Patton, C; et al. BIOLOGICAL BULLETIN Volume: 194 Issue: 1 Pages: 36-43 Published: FEB 1998
An early increase in cGMP follows fertilization of sea urchin eggs, Ciapa, B; Epel, D. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Volume: 223 Issue: 3 Pages: 633-636 Published: JUN 25 1996
Interaction of environmental xenobiotics with a multixenobiotic defense mechanism in the bay mussel Mytilus galloprovincialis from the coast of California, Galgani, F; Cornwall, R; Toomey, BH; et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY Volume: 15 Issue: 3 Pages: 325-331 Published: MAR 1996
PROTEIN-SYNTHESIS INCREASES AFTER FERTILIZATION OF SEA-URCHIN EGGS IN THE ABSENCE OF AN INCREASE IN INTRACELLULAR PH, REES, BB; PATTON, C; GRAINGER, JL; et al. DEVELOPMENTAL BIOLOGY Volume: 169 Issue: 2 Pages: 683-698 Published: JUN 1995
THE IN-VIVO RATE OF GLUCOSE-6-PHOSPHATE-DEHYDROGENASE ACTIVITY IN SEA-URCHIN EGGS DETERMINED WITH A PHOTOLABILE CAGED SUBSTRATE, SWEZEY, RR; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 169 Issue: 2 Pages: 733-744 Published: JUN 1995
CHARACTERIZATION OF MULTIXENOBIOTIC MULTIDRUG TRANSPORT IN THE GILLS OF THE MUSSEL MYTILUS-CALIFORNIANUS AND IDENTIFICATION OF ENVIRONMENTAL SUBSTRATES, CORNWALL, R; TOOMEY, BH; BARD, S; et al. AQUATIC TOXICOLOGY Volume: 31 Issue: 4 Pages: 277-296 Published: APR 1995
MULTIXENOBIOTIC RESISTANCE IN URECHIS-CAUPO EMBRYOS - PROTECTION FROM ENVIRONMENTAL TOXINS, TOOMEY, BH; EPEL, D. BIOLOGICAL BULLETIN Volume: 185 Issue: 3 Pages: 355-364 Published: DEC 1993
YOSIN HEAVY-CHAIN DEPHOSPHORYLATION DURING CYTOKINESIS IN DIVIDING SEA-URCHIN EMBRYOS, LAROCHELLE, DA; EPEL, D. CELL MOTILITY AND THE CYTOSKELETON Volume: 25 Issue: 4 Pages: 369-380 Published: 1993
THE USE OF CAGED SUBSTRATES TO ASSESS THE ACTIVITY OF 6-PHOSPHOGLUCONATE DEHYDROGENASE IN LIVING SEA-URCHIN EGGS, SWEZEY, RR; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 201 Issue: 2 Pages: 366-372 Published: AUG 1992
A RAPID CHANGE IN PHOSPHORYLATION ON TYROSINE ACCOMPANIES FERTILIZATION OF SEA-URCHIN EGGS, CIAPA, B; EPEL, D. FEBS LETTERS Volume: 295 Issue: 1-3 Pages: 167-170 Published: DEC 16 1991
STABLE, RESEALABLE PORES FORMED IN SEA-URCHIN EGGS BY ELECTRIC-DISCHARGE (ELECTROPORATION) PERMIT SUBSTRATE LOADING FOR ASSAY OF ENZYMES INVIVO, SWEZEY, RR; EPEL, D. CELL REGULATION Volume: 1 Issue: 1 Pages: 65-74 Published: NOV 1989
THE LOCALIZATION OF PI AND PIP KINASE-ACTIVITIES IN THE SEA-URCHIN EGG AND THEIR MODULATION FOLLOWING FERTILIZATION, OBERDORF, J; VILARROJAS, C; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 131 Issue: 1 Pages: 236-242 Published: JAN 1989
ENZYME STIMULATION UPON FERTILIZATION IS REVEALED IN ELECTRICALLY PERMEABILIZED SEA-URCHIN EGGS, SWEZEY, RR; EPEL, D. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 85 Issue: 3 Pages: 812-816 Published: FEB 1988
CHANGES IN THE CATALYTIC PROPERTIES OF DNA LIGASES DURING EARLY SEA-URCHIN DEVELOPMENT, PRIGENT, C; MANIEY, D; LEFRESNE, J; et al. DEVELOPMENTAL BIOLOGY Volume: 124 Issue: 1 Pages: 281-286 Published: NOV 1987
KINETICS OF ACTIN ASSEMBLY ATTENDING FERTILIZATION OR ARTIFICIAL ACTIVATION OF SEA-URCHIN EGGS, DUFRESNE, L; SWEZEY, RR; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 172 Issue: 1 Pages: 32-42 Published: SEP 1987
ULTRASTRUCTURAL-LOCALIZATION OF INTRACELLULAR CALCIUM STORES BY A NEW CYTOCHEMICAL METHOD, POENIE, M; EPEL, D. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY Volume: 35 Issue: 9 Pages: 939-956 Published: SEP 1987
REGULATION OF GLUCOSE-6-PHOSPHATE-DEHYDROGENASE ACTIVITY IN SEA-URCHIN EGGS BY REVERSIBLE ASSOCIATION WITH CELL STRUCTURAL ELEMENTS, SWEZEY, RR; EPEL, D. JOURNAL OF CELL BIOLOGY Volume: 103 Issue: 4 Pages: 1509-1515 Published: OCT 1986
THE RELATION BETWEEN INTRACELLULAR PH AND RATE OF PROTEIN-SYNTHESIS IN SEA-URCHIN EGGS AND THE EXISTENCE OF A PH-INDEPENDENT EVENT TRIGGERED BY AMMONIA, DUBE, F; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 162 Issue: 1 Pages: 191-204 Published: JAN 1986
THE HIERARCHY OF REQUIREMENTS FOR AN ELEVATED INTRACELLULAR PH DURING EARLY DEVELOPMENT OF SEA-URCHIN EMBRYOS, DUBE, F; SCHMIDT, T; JOHNSON, CH; et al. CELL Volume: 40 Issue: 3 Pages: 657-666 Published: 1985
CHARACTERIZATION OF A CA-2+-STIMULATED LIPID PEROXIDIZING SYSTEM IN THE SEA-URCHIN EGG, PERRY, G; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 107 Issue: 1 Pages: 47-57 Published: 1985
FERTILIZATION STIMULATES LIPID-PEROXIDATION IN THE SEA-URCHIN EGG, PERRY, G; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 107 Issue: 1 Pages: 58-65 Published: 1985
INVOLVEMENT OF ZINC IN THE REGULATION OF PHI, MOTILITY, AND ACROSOME REACTIONS IN SEA-URCHIN SPERM, CLAPPER, DL; DAVIS, JA; LAMOTHE, PJ; et al. JOURNAL OF CELL BIOLOGY Volume: 100 Issue: 6 Pages: 1817-1824 Published: 1985
SPERM MOTILITY IN THE HORSESHOE-CRAB .5. ZINC REMOVAL MEDIATES CHELATOR INITIATION OF MOTILITY, CLAPPER, DL; LAMOTHE, PJ; DAVIS, JA; et al. JOURNAL OF EXPERIMENTAL ZOOLOGY Volume: 236 Issue: 1 Pages: 83-91 Published: 1985
THE LIMULUS SPERM MOTILITY-INITIATING PEPTIDE INITIATES ACROSOME REACTIONS IN SEA-WATER LACKING POTASSIUM, CLAPPER, DL; EPEL, D. JOURNAL OF EXPERIMENTAL ZOOLOGY Volume: 236 Issue: 2 Pages: 211-217 Published: 1985
CORTICAL VESICLE EXOCYTOSIS IN ISOLATED CORTICES OF SEA-URCHIN EGGS - DESCRIPTION OF A TURBIDOMETRIC ASSAY AND ITS UTILIZATION IN STUDYING EFFECTS OF DIFFERENT MEDIA ON DISCHARGE, SASAKI, H; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 98 Issue: 2 Pages: 327-337 Published: 1983
CHANGES IN INTRACELLULAR ACIDIC COMPARTMENTS IN SEA-URCHIN EGGS AFTER ACTIVATION, LEE, HC; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 98 Issue: 2 Pages: 446-& Published: 1983
A VOLATILE INHIBITOR IMMOBILIZES SEA-URCHIN SPERM IN SEMEN BY DEPRESSING THE INTRACELLULAR PH, JOHNSON, CH; CLAPPER, DL; WINKLER, MM; et al. DEVELOPMENTAL BIOLOGY Volume: 98 Issue: 2 Pages: 493-501 Published: 1983
CHANGES IN INTERNAL PH ASSOCIATED WITH INITIATION OF MOTILITY AND ACROSOME REACTION OF SEA-URCHIN SPERM, LEE, HC; JOHNSON, C; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 95 Issue: 1 Pages: 31-45 Published: 1983
HIGH HYDROSTATIC-PRESSURE AND THE DISSECTION OF FERTILIZATION RESPONSES .1. THE RELATIONSHIP BETWEEN CORTICAL GRANULE EXOCYTOSIS AND PROTON EFFLUX DURING FERTILIZATION OF THE SEA-URCHIN EGG, SCHMIDT, T; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 146 Issue: 2 Pages: 235-248 Published: 1983
HEAVY-METAL CHELATORS PROLONG MOTILITY AND VIABILITY OF SEA-URCHIN SPERM BY INHIBITING SPONTANEOUS ACROSOME REACTIONS, JOHNSON, CH; EPEL, D. JOURNAL OF EXPERIMENTAL ZOOLOGY Volume: 226 Issue: 3 Pages: 431-440 Published: 1983
STIMULATION OF PROTEIN-PHOSPHORYLATION DURING FERTILIZATION-INDUCED MATURATION OF URECHIS-CAUPO OOCYTES, MEIJER, L; PAUL, M; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 94 Issue: 1 Pages: 62-70 Published: 1982
STARFISH OOCYTE MATURATION AND FERTILIZATION - INTRACELLULAR PH IS NOT INVOLVED IN ACTIVATION, JOHNSON, CH; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 92 Issue: 2 Pages: 461-469 Published: 1982
IS THERE A ROLE FOR THE CA-2+ INFLUX DURING FERTILIZATION OF THE SEA-URCHIN EGG, SCHMIDT, T; PATTON, C; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 90 Issue: 2 Pages: 284-290 Published: 1982
SPERM MOTILITY IN THE HORSESHOE-CRAB .3. ISOLATION AND CHARACTERIZATION OF A SPERM MOTILITY INITIATING PEPTIDE, CLAPPER, DL; EPEL, D. GAMETE RESEARCH Volume: 6 Issue: 4 Pages: 315-326 Published: 1982
SPERM MOTILITY IN THE HORSESHOE-CRAB .4. EXTRACELLULAR IONS AND INTRACELLULAR PH ARE NOT MEDIATORS OF MOTILITY INITIATION, CLAPPER, DL; EPEL, D. GAMETE RESEARCH Volume: 6 Issue: 4 Pages: 327-342 Published: 1982
CALMODULIN ACTIVATES NAD KINASE OF SEA-URCHIN EGGS - AN EARLY EVENT OF FERTILIZATION, EPEL, D; PATTON, C; WALLACE, RW; et al. CELL Volume: 23 Issue: 2 Pages: 543-549 Published: 1981
THE APPEARANCE OF AN EXTRACELLULAR ARYLSULFATASE DURING MORPHOGENESIS OF THE SEA-URCHIN STRONGYLOCENTROTUS-PURPURATUS, RAPRAEGER, AC; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 88 Issue: 2 Pages: 269-278 Published: 1981
CA2+-STIMULATED PRODUCTION OF H2O2 FROM NAPHTHOQUINONE OXIDATION IN ARBACIA EGGS, PERRY, G; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 134 Issue: 1 Pages: 65-72 Published: 1981
INTRACELLULAR PH OF SEA-URCHIN EGGS MEASURED BY THE DIMETHYLOXAZOLIDINEDIONE (DMO) METHOD, JOHNSON, CH; EPEL, D. JOURNAL OF CELL BIOLOGY Volume: 89 Issue: 2 Pages: 284-291 Published: 1981
FERTILIZATION, EPEL, D. ENDEAVOUR Volume: 4 Issue: 1 Pages: 26-31 Published: 1980
CALCIUM-MEDIATED MITOCHONDRIAL MOVEMENT IN ASCIDIAN SPERM DURING FERTILIZATION, LAMBERT, CC; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 69 Issue: 1 Pages: 296-304 Published: 1979
ROLE OF CA+2 IN TRIGGERING DEVELOPMENT AT FERTILIZATION, EPEL, D; NISHIOKA, D; PERRY, G. BIOLOGIE CELLULAIRE Volume: 32 Issue: 1 Pages: 135-140 Published: 1978
FLAGELLAR MOTILITY IS NOT INVOLVED IN INCORPORATION OF SPERM INTO EGG AT FERTILIZATION, EPEL, D; CROSS, NL; EPEL, N. DEVELOPMENT GROWTH & DIFFERENTIATION Volume: 19 Issue: 1 Pages: 15-21 Published: 1977
NOVEL PROCEDURE FOR OBTAINING DENUDED SEA-URCHIN EGGS AND OBSERVATIONS ON ROLE OF VITELLINE LAYER IN SPERM RECEPTION AND EGG ACTIVATION, CARROLL, EJ; BYRD, EW; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 108 Issue: 2 Pages: 365-374 Published: 1977
ROLE OF CALCIUM-IONS IN ACROSOME REACTION OF SEA-URCHIN SPERM - REGULATION OF EXOCYTOSIS, COLLINS, F; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 106 Issue: 1 Pages: 211-222 Published: 1977
PROGRAM OF FERTILIZATION, EPEL, D. SCIENTIFIC AMERICAN Volume: 237 Issue: 5 Pages: 128-& Published: 1977
GLUTATHIONE THIOL-DISULFIDE STATUS IN SEA-URCHIN EGG DURING FERTILIZATION AND 1ST CELL-DIVISION CYCLE, FAHEY, RC; MIKOLAJCZYK, SD; MEIER, GP; et al. BIOCHIMICA ET BIOPHYSICA ACTA Volume: 437 Issue: 2 Pages: 445-453 Published: 1976
SCANNING ELECTRON-MICROSCOPE STUDIES OF SEA-URCHIN FERTILIZATION .1. EGGS WITH VITELLINE LAYERS, TEGNER, MJ; EPEL, D. JOURNAL OF EXPERIMENTAL ZOOLOGY Volume: 197 Issue: 1 Pages: 31-& Published: 1976
INTRACELLULAR PH AND ACTIVATION OF SEA-URCHIN EGGS AFTER FERTILIZATION, JOHNSON, JD; EPEL, D; PAUL, M. NATURE Volume: 262 Issue: 5570 Pages: 661-664 Published: 1976
PROGRAM OF AND MECHANISMS OF FERTILIZATION IN ECHINODERM EGG, EPEL, D. AMERICAN ZOOLOGIST Volume: 15 Issue: 3 Pages: 507-522 Published: 1975
ISOLATION AND BIOLOGICAL-ACTIVITY OF PROTEASES RELEASED BY SEA-URCHIN EGGS FOLLOWING FERTILIZATION, CARROLL, EJ; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 44 Issue: 1 Pages: 22-32 Published: 1975
FORMATION OF FERTILIZATION ACID BY SEA-URCHIN EGGS DOES NOT REQUIRE SPECIFIC CATIONS, PAUL, M; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 94 Issue: 1 Pages: 1-6 Published: 1975
RELATIONSHIP BETWEEN RELEASE OF SURFACE PROTEINS AND METABOLIC ACTIVATION OF SEA-URCHIN EGGS AT FERTILIZATION, JOHNSON, JD; EPEL, D. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 72 Issue: 11 Pages: 4474-4478 Published: 1975
POLYSPERMY BLOCK OF SPISULA EGGS IS PREVENTED BY CYTOCHALASIN-B, ZIOMEK, CA; EPEL, D. SCIENCE Volume: 189 Issue: 4197 Pages: 139-141 Published: 1975
ANALYSIS OF PARTIAL METABOLIC DEREPRESSION OF SEA-URCHIN EGGS BY AMMONIA - EXISTENCE OF INDEPENDENT PATHWAYS, EPEL, D; STEINHARDT, R; HUMPHREYS, T; et al. DEVELOPMENTAL BIOLOGY Volume: 40 Issue: 2 Pages: 245-255 Published: 1974
PROTEIN-SYNTHESIS DURING HORMONALLY INDUCED MEIOTIC MATURATION AND FERTILIZATION IN STARFISH OOCYTES, HOUK, MS; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 40 Issue: 2 Pages: 298-310 Published: 1974
SEA-URCHIN EGG FERTILIZATION STUDIED WITH A FLUORESCENT-PROBE (ANS), FINEGOLD, L; BAKER, EA; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 86 Issue: 2 Pages: 248-252 Published: 1974
IS CALCIUM IONOPHORE A UNIVERSAL ACTIVATOR FOR UNFERTILIZED EGGS, STEINHAR.RA; EPEL, D; CARROLL, EJ; et al. NATURE Volume: 252 Issue: 5478 Pages: 41-42 Published: 1974
ACTIVATION OF SEA-URCHIN EGGS BY A CALCIUM IONOPHORE, STEINHAR.RA; EPEL, D. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 71 Issue: 5 Pages: 1915-1919 Published: 1974
STUDIES OF OOGENESIS IN URECHIS-CAUPO .2. ACCUMULATION DURING OOGENESIS OF CARBOHYDRATE, RNA, MICROTUBULE PROTEIN, AND SOLUBLE, MITOCHONDRIAL, AND LYSOSOMAL ENZYMES, MILLER, JH; EPEL, D. DEVELOPMENTAL BIOLOGY Volume: 32 Issue: 2 Pages: 331-344 Published: 1973
PROTEASE RELEASED FROM SEA-URCHIN EGGS AT FERTILIZATION ALTERS VITELLINE LAYER AND AIDS IN PREVENTING POLYSPERMY, VACQUIER, VD; TEGNER, MJ; EPEL, D. EXPERIMENTAL CELL RESEARCH Volume: 80 Issue: 1 Pages: 111-119 Published: 1973
EFFECTS OF CHLORINATION OF WASTEWATER ON FERTILIZATION IN SOME MARINE INVERTEBRATES, MUCHMORE, D; EPEL, D. MARINE BIOLOGY Volume: 19 Issue: 2 Pages: 93-95 Published: 1973
SEA-URCHIN SPERM-EGG INTERACTIONS STUDIED WITH SCANNING ELECTRON-MICROSCOPE, TEGNER, MJ; EPEL, D. SCIENCE Volume: 179 Issue: 4074 Pages: 685-688 Published: 1973